Science and Products

Topas Therapeutics develops nanoparticles loaded with antigenic peptides. These conjugates mimic blood borne antigens that are taken up by liver sinusoidal endothelial cells (LSECs), which present them to T cells under tolerogenic conditions. The antigenic peptides are recognized by T cells, and they can be derived from autoantigens, allergens or drugs. Accordingly, Topas develops products in the areas of autoimmune diseases, allergies and ADA (anti-drug antibodies).